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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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TCS 21311 is a small-molecule inhibitor of Janus kinase 3 (JAK3) used as a biochemical and pharmacological tool. It exhibits potent enzymatic activity (IC50 ≈ 8 nM) and strong selectivity for JAK3 over JAK1, JAK2, and TYK2, making it suitable for studies of JAK3-mediated signaling.
Potent JAK3 inhibition with an IC50 of approximately 8 nM.
Greater than 100-fold selectivity versus JAK1, JAK2, and TYK2.